Microcytic hypochromic RBCs on peripheral smear — but MCV may overlap with thalassemia
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Must investigate source of blood loss: menstrual history, GI bleed evaluation (occult blood, colonoscopy if age > 45)
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Oral iron (ferrous sulfate 325mg) on empty stomach with vitamin C — recheck ferritin at 8-12 weeks
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GI side effects common — if intolerant, switch to ferrous gluconate or IV iron
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